Hi BP,
There are several options.
You can but "Streets and Trips" (Microsoft)
http://www.microsoft.com/streets/default.mspx , together with a GPS receiver, and use it in a notebook in your car.
Or you can buy a portable GPS receiver (Magellan), and carry it in your car. There's a model with speech synthesis that will talk to you as you're driving, and guide you to your final destination.
Or buy one of the new cars with included GPS system
That last option is very cool

A friend of mine bought his wife a new SUV, and it has just that

It even "beeps" just prior to left/right turns you have to make, and guides you with voice all the way to your target.
I think the best option is to buy the magellan, because it's portable, it includes maps, and there's a voice model.
http://www.magellangps.com/en/produc...DID=955&bhcp=1
-kwag