Actually, the best thing to use for both Virus and spyware is Symantec
Anti-Virus Corporate Editon V.10. Cleans and protects against just about everything. Of course you need to shell out some $$$ to get it, but I've never had to worry about virus or spyware with it
If you need something cheaper that does a good job on spyware/adware the go to Webroot's website and look into spysweeper. It does a pretty good job as well. Can't say I've ever liked Norton
's home/residental/consumer stuff.